Perhaps a little over many of our heads, I did find this article to be a good read with lots of useful references for us to follow up. Even if one is a lone wolf still tinkering with JS and jQuery, it is nonetheless a valuable guide to the future giving us lots of directions to turn as our skill level improves.
It's a fantastic read. Thought it was going to be yet another long list of JS frameworks etc. but instead it's a very well-thought out roadmap and one I've definitely bookmarked for future reference.
And here's another great read for you @mtf if you've not seen it yet: